Suicidal Ideation and Ketamine-Assisted Therapy

woman interacts with glimmers of light through her window, suicidal ideation and ketamine assisted therapy

Suicidal ideation is a complex and distressing experience that, first and foremost, requires timely intervention, as well as compassionate understanding and access to effective care. To help those struggling, It’s critical to recognize the warning symptoms. Once identified, individuals suffering from self-harming thoughts can benefit from various treatment options, including innovative approaches like ketamine-assisted therapy (KAT).

Understanding Suicidal Ideation


Suicidal ideation is the term used to describe having thoughts of taking one’s own life. These thoughts can stem from various underlying factors, such as mental health disorders, trauma, substance use, or feelings of hopelessness and isolation. Recognizing these signs early on can play a pivotal role in preventing potential self-harm.

Being aware of the warning indicators of suicidal ideation is essential for dealing with the condition properly. Friends, family members, and loved ones should be aware of behavioral changes and open lines of communication. It’s critical to show empathy and take someone’s expressed suicidal ideas seriously.

Suicidal ideation can manifest in many behaviors and mood changes. Some common behaviors associated with suicidal thoughts include increased substance use, researching methods of self-harm, social withdrawal, significant changes in sleep patterns, reaching out to say goodbye, giving away possessions, and displaying signs of aggression or fatigue. Additionally, individuals experiencing suicidal ideation often exhibit changes in mood, such as depression, anxiety, loss of interest, irritability, humiliation, agitation, anger, or relief.

Treatment Options for Suicidal Ideation


When treating suicidal ideation, it is essential to seek immediate professional help.

1. Timely Intervention in a Crisis

During a suicidal crisis, immediate action is vital. In extreme cases, hospitalization might be necessary to ensure the person’s safety. Additionally, having a 24/7 crisis helpline number readily available can provide individuals with access to professionals who can offer guidance and refer them to appropriate care facilities.

2. Psychotherapy

Psychotherapy, particularly Cognitive Behavioral Therapy (CBT), can effectively treat suicidal ideation. Therapists work with individuals to identify negative thought patterns and develop coping strategies. CBT helps individuals regain control over their thoughts and emotions, reducing the intensity of suicidal ideation.

3. Ketamine-Assisted Therapy

Ketamine-assisted therapy has shown promise in addressing treatment-resistant depression and suicidal ideation. Research studies have highlighted the rapid and beneficial effects of ketamine infusions for individuals with treatment-resistant depression (TRD) and suicidality. These studies have demonstrated significant reductions in depressive symptoms and suicidal ideation. KAT can rapidly alleviate symptoms of depression and anxiety, offering a window of relief during which the individual can engage more effectively in therapy and other interventions.

The Impact of IV Ketamine on Suicidal Ideation


A recent study published in The BMJ Journal has reinforced the safety and effectiveness of IV Ketamine as a rapidly efficient solution for individuals grappling with suicidal ideation. In particular, these findings indicate that ketamine holds particular promise for those facing high suicidal risk.

Improvement in suicidal ideation following IV ketamine treatment is closely linked to, though not entirely driven by, improvements in depression and anxiety. Within this study, researchers emphasize the significance of ketamine’s analgesic, or pain relieving, properties. Ketamine’s interaction with the brain’s NMDA receptors results in the dampening of pain perception. This modulation of pain pathways extends its impact on mood regulation and cognitive processes, effectively alleviating symptoms of depression and anxiety. By strategically engaging and adjusting these receptors, ketamine can disrupt the cycle of negative thought patterns associated with these conditions.

Supporting Someone in Crisis:
What to Do When Someone Expresses Self-Harm Ideation


If a friend or loved one expresses interest in self-harm, responding with empathy and taking immediate action is critical. Access to professional treatment and guidance is essential to ensuring their safety and well-being. Here are a few steps to take that might help you navigate the situation:

1.Stay Calm and Listen

When someone confides in you about their self-harm thoughts, remain calm and non-judgmental. Offer a safe space for them to express their feelings without interruption. Listening attentively shows that you care and are ready to support them.

2. Express Concern and Ask Open-ended Questions

Gently express your concern for their well-being. Ask open-ended questions to encourage them to share their feelings and thoughts more deeply. Avoid making judgments or minimizing their experiences.

3. Encourage Professional Help

Urge your friend or loved one to seek professional help. Help them source contact information for crisis helplines, mental health hotlines, or therapists who specialize in dealing with self-harm ideation. Motivate them by assisting in making appointments or finding suitable resources.

4. Remove Immediate Hazards

If there are immediate threats to their safety, such as access to harmful objects, collaborate with them to remove these hazards from their environment. Stay with them or find someone else who can until they’re safe.

5. Call for Help

Call the National Suicide Prevention Lifeline (800-273-8255) or the Crisis Text Line (text HOME to 741741). These helplines are available 24/7 to provide assistance and guidance. You need not be the person in crisis to call. This line is staffed by trained professionals who can help you. If you know the person’s whereabouts, you may also call 911, and an ambulance will be dispatched.

Final Thoughts


Understanding and addressing suicidal ideation requires a multifaceted approach. Timely intervention is crucial in crisis situations, offering immediate support and access to care. Psychotherapy equips individuals with coping strategies to manage their thoughts and emotions. Additionally, innovative treatments like ketamine-assisted therapy hold promise in providing rapid relief for those who are struggling. By offering a combination of compassionate support, professional guidance, and access to effective treatments, we can work towards reducing the devastating impact of suicidal ideation and helping individuals find hope and healing.


If you or someone you love is in immediate danger, it is crucial to reach out for help. Contact the National Suicide Prevention Lifeline (800-273-8255) or the Crisis Text Line (text HOME to 741741).


Discover What Psychedelic Medicine Can Do for You

To transcend depression, anxiety, alcohol use disorders, and trauma-induced mood disorders, Nushama offers IV ketamine for an ego-dissolving psychedelic experience. A holistic path of mindful intention setting, ketamine journeys, and thoughtful integration in safe, healing-focused settings empower members to reset and reconnect.

Explore Our Blog